Well Armor Destructor only debuffs the enemies' DP which will not affect your damage at all.
Lock-On lowers HV, and only raises your damage by a few hundred at most.
The only debuff that I find useful is Shield Breaker. It double your damage, and makes it possible to kill those darn Red Salamanders.
There is also Sticky Foot. Which lowers Hv based on your DA. Doesnt really do much if you dont have good DA
And if you're going Hybrid or are already Hybrid theres Sticky Icky. It lowers DP,HV,and LK Im not sure how good Sticky Icky is havent gotten it yet.
Jewlia: Ruby/Pearl Server
DanTheLion- Lv. 20x Hybrid Lion